Gamma-Aminobutyric Acid

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Role Of Gamma-Aminobutyric Acid (GABA) in the body

  • SUPPORTS NATURAL RELAXATION — works with your mind and body when you're experiencing occasional stress, assisting your brain's primary calming neurotransmitter pathway

  • ENHANCES STRESS RESILIENCE — helps maintain mental energy during challenging situations, supporting you when navigating daily challenges during perimenopause

  • MAINTAINS COGNITIVE CLARITY — supports clear thinking and concentration, while promoting a relaxed mental state

Why We Use It

Gamma Aminobutyric Acid (GABA) - PharmaGABA®

GABA is your brain's primary calming neurotransmitter, essentially a mental brake pedal that helps regulate excessive brain activity, and supports relaxation while maintaining focus. Our Midlife Essentials includes PharmaGABA®, created through the natural fermentation process of growing Lactobacillus hilgardii bacteria. This form is identical to what your brain naturally produces, allowing it to work with your body's own systems effectively.

We chose PharmaGABA® for Midlife Essentials because of the strong clinical research on this material specifically. The brain wave monitoring studies demonstrate that 100mg of PharmaGABA® supports healthy alpha-to-beta ratios within 60 minutes after ingesting. Supporting healthy levels of the ‘calming’ alpha waves can be helpful during times of increased stress when beta waves may be more activated, leading to a more restless mind and anxious thoughts.

The change in brain wave state, from beta to alpha, creates an environment where your brain can handle life's challenges with clarity and a sense of calm. This means you experience a measurable shift toward calm, focused thinking.

Research also shows PharmaGABA® supports a healthy stress response by helping maintain mental energy during challenging situations, with participants showing greater resilience compared to placebo during demanding tasks. This means you’re likely to feel more centered and grounded in your everyday obligations.

In Your Formula

You’ll find Gamma-Aminobutyric Acid (GABA) in:

References

  • Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans

    Abdou AM, Higashiguchi S, Horie K, Kim M, Hatta H, Yokogoshi H. Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. Biofactors. 2006;26(3):201-8.

  • Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks

    Yoto A, Murao S, Motoki M, et al. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks. Amino Acids. 2012;43(3):1331-1337.

  • Improvement of Memory and Spatial Cognitive Function by Continuous Ingestion of 100 mg/day of γ-Aminobutyric Acid (GABA)

    Yamatsu A, Nakamura U, Saddam HM, et al. Improvement of Memory and Spatial Cognitive Function by Continuous Ingestion of 100 mg/day of γ-Aminobutyric Acid (GABA). Jpn Pharmacol Ther. 2020;48(3):475-86.

  • Gamma-Aminobutryric Acid (GABA)

    Gamma-Aminobutryric Acid (GABA), Monograph. Altern Med Rev. 2007. Sep;12(3):274-9.

  • Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid

    Kanehira T, Nakamura Y, Nakamura K, Horie K, Horie N, Furugori K, Sauchi Y, Yokogoshi H. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid. J Nutr Sci Vitaminol (Tokyo). 2011;57(1):9-15.