Primary Essentials

Primary Essentials

Feel energized today. Clearer mood and less symptoms of PMS in weeks. Glowing skin and balanced cycles in two months.

From /Day SachetsAge: 18-45
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The most important part of supplementation is consistency!

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    Includes critical nutrients

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    Eases PMS & menstrual discomfort

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    Balances mood throughout your cycle

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    Supports energy metabolism

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    Enhances skin radiance from within

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    Nourishes digestive health & microbiome

Key ingredients include:

  • All essential vitamins, including A, C, D, E, K and a full B-complex
  • Calcium, Chromium, Iron, and Magnesium
  • Affron® saffron extract
  • Pomella® pomegranate extract
  • Chasteberry extract
  • Probiotics (Unique-IS2®)
  • Choline
  • Electrolytes

Supplement Facts

Here's how Primary Essentials typically works over time:

Weeks 2-3: You may start to notice more energy support from the B-complex vitamins and electrolytes

Week 4: Mood stability from Affron® saffron 

Month 2: Gut health benefits and microbiome improvement from Bacillus coagulans Unique-IS2®; increased skin radiance from Pomella® pomegranate extract

Month 2-3: PMS support from chasteberry including relief from physical discomfort, breast tenderness and hormonal mood swings

Month 3+:  The full effects of essential nutrients like vitamin D3, iron and choline, as well as clinically-studied ingredients will be felt and sustained with consistent on-going use

Pour contents of one sachet into a glass. Add 8-12 oz of water, stir, and enjoy with a straw. Alternatively, swirl the glass before the last couple sips as natural settling will occur. Take at least once daily (with or without food).

Our Medical Advisory Board formulated Primary Essentials to match published research at dosages proven to deliver results for women. This is uncommon in the supplement world–brands typically sprinkle many ingredients in too-small quantities.

Manufactured in US-based facilities at FDA registered sites, with cGMP certifications.We use third-party testing for independent verification of our quality. Ingredients included are Generally Recognized as Safe (GRAS). Our products are: 

  • Non-GMO
  • Gluten-free
  • Vegetarian*
  • No artificial flavors or colors
  • No sugar added

*contains shellac, a natural resin sourced from the Lac beetle

Designed to replace multiple supplements with one comprehensive solution for your hormonal stage.

Science & Research

Formulated with Purpose. Backed by Science.

Every ingredient in Primary Essentials was selected by our Medical Advisory Board to address the real health concerns women experience during cycling years while also ensuring overall nutritional needs are met.

58%

Reduction in Mood Disturbance Scores in four weeks [1]

20%

Improvement in sleep quality ratings in 28 days [2]

43%

Reduction in menstrual distress scores [3]

98%

Achieved normal stool consistency after 4 weeks [4]

Enhanced Absorption

Lifestage Specific

Science Backed Ingredients

Comprehensive Formula

Published In:
[1] Complementary Therapies in Medicine (Volume 33, August 2017). [2] Sleep Medicine (Volume 86, October 2021). [3] Archives of Gynecology and Obstetrics (Volume 264, 2000). [4] Probiotics and Antimicrobial Proteins (June 2020).

What’s inside

Our clinically backed ingredients

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MAXIMAL ABSORPTION. GENUINE DAILY ENJOYMENT.

What’s inside

Our clinically backed ingredients

Botanicals & Other Clinically-Backed Ingredients

PMS and cycle-related symptoms affect up to 85% of cycling-age women. We've included 40mg of chasteberry extract, shown in the research to significantly reduce breast tenderness, bloat, and mood changes associated with PMS. Combined with 28mg affron® saffron extract for mood support throughout the cycle, and 250mg Pomella® pomegranate extract for skin health, this comprehensive botanical blend replaces multiple cycle-support supplements with clinically-studied ingredients at research-backed dosages.

Ingredients Glossary
Clear plastic cup with red liquid on a red background Saffron Extract
Clear plastic cup with red liquid on a red background Pomegranate Extract
Clear plastic cup with red liquid on a red background Chasteberry Extract

Probiotics

Our clinically studied probiotic strain of Bacillus coagulans Unique-IS2® supports digestive health and stool regularity, and promotes a healthy microbiome that may help with nutrient availability for the gut cells and overall nutrient absorption. Gut health affects hormone metabolism and the gut-brain connection—the communication pathway between your digestive system and brain that influences mood, stress response, and energy levels throughout your cycle. Since your gut produces about 90% of your body's serotonin (a key mood neurotransmitter), supporting gut health directly impacts how you feel during your cycle including how severely you experience PMS.

Ingredients Glossary
Clear plastic cup with red liquid on a red background Bacillus Coagulans

Vitamins & Minerals

Cycling women have specific nutritional needs, including higher iron requirements due to the significant iron loss during regular menstruation. Our formula provides methylated B-vitamin complex, bioavailable iron, and other essential vitamins and minerals in forms your body can readily use. These nutrients are in their bioactive form that your body needs during this phase of life in dosages that matter, letting you eliminate the need for a separate multivitamin, iron supplement, and B-complex formula while providing targeted support for your menstrual cycle.

Ingredients Glossary
Clear plastic cup with red liquid on a red background Iron
Clear plastic cup with red liquid on a red background B-Vitamin Complex
Clear plastic cup with red liquid on a red background Vitamin K2
Clear plastic cup with red liquid on a red background Vitamin D3

Electrolytes

Our electrolyte blend (200mg sodium, 100mg potassium) supports optimal hydration and nervous system function when made into a beverage. Unlike hydration products with up to 1000mg of sodium, our formulation delivers an amount more suitable without excess sodium that may cause bloating.

Ingredients Glossary
Clear plastic cup with red liquid on a red background Sodium
Clear plastic cup with red liquid on a red background Potassium

How we compare

Biologica Essentials deliver comprehensive nutrition and targeted relief, all designed for the woman who you are today.

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Greens

Multivitamins

Probiotics

Designed For Female Lifestages

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Alleviates Key Health Concerns

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Essential Vitamins and Minerals

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Clinically Studied Dosages

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Supports Gut Health

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Electrolytes

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WHAT’S BEHIND OUR LIFESTAGE FORMULATIONS

THE SCIENCE OF YOUR PRIME CYCLING YEARS

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Natural monthly hormonal fluctuations are normal for cycling women, but can also cause a whole host of symptoms, everything from mood to energy to skin health. Primary Essentials provides targeted nutrition for this dynamic life stage, with ingredients that support your body through natural cycle variations, rather than trying to combat them.

Learn more — hormones 101

TASTES LIKE A DAILY RITUAL SHOULD

We tested dozens of flavors because your daily supplement shouldn't taste like medicine. As a result of this research, and without any sugar, each Biologica Essential comes in a range of indulgent, flavor-forward options from fruit from real farms—think bright, juicy, and never too sweet. It's the kind of daily ritual you'll actually want to maintain.

Product Reviews

4.8
Rated 4.8 out of 5 stars
Based on 73 reviews
100%would recommend this product
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73 reviews
  • M
    Miranda
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Loved this!

    This is such an amazing multivitamin! It honestly covers everything I need without the stress of getting tons of supplements for the same benefit.

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  • R
    Rachael
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Better energy and mood

    Since having my daughter two years ago I have struggled with hormone balance. I decided to try Biological far I am seeing improvements in fluid retention, bloating, mood swings and sustained energy levels. I have been surprised by my wonderful luck with this product

    Was this helpful?
  • A
    Amanda
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    5 stars

    5 stars

    Was this helpful?
  • L
    Laure
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    2 weeks ago
    New customer

    I love the ingredients and beautiful packaging. I have only taken it for about a week now, not feeling any difference yet. The flavors are ok, could be better but not a huge issue. What bothers me more is the grittiness and it never fully dissolves. I don’t like how you have to keep mixing it before each sip, and that last sip is full of grit. I honestly would prefer a pill if all these ingredients could be shoved into a capsule. I’ll keep taking it and see if I feel any difference, I ordered a 3 month supply

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  • ED
    Emily d.
    I recommend this product
    Rated 5 out of 5 stars
    3 weeks ago
    Incredible Product that Makes Life SO Much Easier!

    This is an incredible product! I was really impressed with the format & taste.

    Format: love how the powder is effervescent/fizzy and that it completely dissolves. I find sometimes supplements like electrolytes or even creatine can be "chunky" which makes it much less appetizing. All you do is pour it into a glass of water, let it fizz, and it's ready to go. The on the go packs are also a life saver (anyone on a supplements regimen knows how grueling packing all of those and taking them while traveling can be)

    Taste: loved the cranberry lemonade taste! No weird after-taste, and doesn't taste "fake" like many others who pump full of artificial flavorings/fake sweeteners.

    Excited to try other flavors!!!

    Was this helpful?

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Frequently Asked Questions

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Citations

58% Reduction in Mood Disturbance Scores in four weeks

"affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial."

  • Authors: Kell, G., Rao, A., Beccaria, G., Clayton, P., et al.
  • Published In: Complementary Therapies in Medicine (Volume 33, August 2017).
  • The 58% Statistic: the 58% figure is a commonly cited calculation from this specific trial's data. It represents the percentage decrease in the Total Mood Disturbance (TMD) score for participants taking the 28 mg/day dose compared to their baseline after 4 weeks.

20% Improvement in sleep quality ratings in 28 days

"An investigation into an evening intake of a saffron extract (affron®) on sleep quality, cortisol, and melatonin concentrations in adults with poor sleep: a randomised, double-blind, placebo-controlled, multi-dose study."

  • Authors: Lopresti, A. L., Smith, S. J., & Drummond, P. D.
  • Published In: Sleep Medicine (Volume 86, October 2021).
  • The 20% Statistic: refers to a 20% increase in the Restorative Sleep Questionnaire (RSQ) score after 28 days of supplementation. The RSQ measures how "restored" or energized a person feels upon waking, rather than just the number of hours they slept.

43% Reduction in menstrual distress scores

"Efficacy of Vitex agnus castus L. extract Ze 440 in patients with pre-menstrual syndrome (PMS)."

  • Authors: Berger, D., Schaffner, W., Schrader, E., et al.
  • Published In: Archives of Gynecology and Obstetrics (Volume 264, 2000).
  • The 43% Statistic: this figure (rounded from 42.5% in the raw data) represents the average reduction in the Moos' Menstrual Distress Questionnaire (MMDQ) scores after three months of treatment.

98% Achieved normal stool consistency after 4 weeks

"Bacillus coagulans Unique IS2 in Constipation: A Double-Blind, Placebo-Controlled Study."

  • Authors: Madempudi, R. S., Neelamraju, J., Ahire, J. J., Gupta, S. K., & Shukla, V. K.
  • Published In: Probiotics and Antimicrobial Proteins (June 2020).
  • The 98% Statistic: at the start of the study, 0% of the participants had normal stool consistency. By the end of 4 weeks, 98% of those in the probiotic group achieved "normal" stool form (defined as Type 3, 4, or 5 on the Bristol Stool Chart).