Postmenopause Essentials

Improved digestion. Heightened energy. Bone, heart, and skin health. Everything you need in drinkable multivitamin formulated exclusively for postmenopausal women.

From /Day SachetsAge: 50+
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The most important part of supplementation is consistency!

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    Includes critical nutrients

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    Supports lean muscle mass

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    Promotes cellular health & longevity

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    Supports energy metabolism, heart & bone health

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    Enhances skin radiance from within

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    Nourishes digestive health & microbiome

Product Description

Your postmenopause years deserve more than generic multivitamins. Postmenopause Essentials delivers clinically-studied powerhouses like Chromax® chromium, hobamine® 2-HOBA, and Pomella® pomegranate built on a foundation of bioavailable essential vitamins and minerals at meaningful dosages, plus probiotics and electrolytes—all in one comprehensive daily formula supporting lean muscle mass, cellular health, and skin radiance.

Postmenopause Essentials includes a comprehensive suite of vitamins and minerals, plus premium ingredients backed by published research:

  • Chromax® Chromium Picolinate (200mcg): Clinically shown to support lean muscle mass and metabolism, in a highly bioavailable form
  • hobamine® 2-HOBA (100mg): Clinically-studied compound that has been shown to support signaling molecules associated with cellular health and healthy aging
  • Pomella® Pomegranate Extract (300mg): Clinical studies show an improvement in skin hydration and a small reduction in wrinkles
  • Complete bone health complex: Vitamin D3, K2, calcium, and magnesium eliminate the need for separate bone-specific supplements
  • Essential vitamin and mineral complex: High-quality, easily absorbable nutrients that eliminate the need for a separate multivitamin
  • Probiotics (Bacillus coagulans IS2): Clinically studied strain that supports the digestive system and a healthy microbiome replaces standalone digestive supplements
  • Balanced electrolytes: Support optimal hydration once added to water, and nervous-muscle system function

Key ingredients include:

  • All essential vitamins, including A, C, D, E, K and a full B-complex
  • Calcium
  • Magnesium
  • Chromax® Chromium Piccolinate
  • hobamine®
  • Pomella® pomegranate extract
  • Probiotics (Unique-IS2®)
  • Choline (110mg)
  • Electrolytes

Supplement Facts

Here's how Postmenopause Essentials typically works over time:

Weeks 2-3: You may start to notice more energy from the B-complex vitamins and electrolytes

Weeks 5-8: hobamine® is supporting cellular health, helping to combat oxidative stress and assist with longevity 

Month 2: Gut health benefits and microbiome improvement from Bacillus coagulans Unique-IS2®; increased skin radiance from Pomella® pomegranate extract 

Month 2-3: Chromax® is helping to support a healthy metabolism and lean muscle mass, paired with diet and exercise

Month 3+: The full effects of essential nutrients like vitamin D3, calcium, and K2 for bone health, as well as other clinically-studied ingredients will be felt and sustained with consistent use

Pour contents of one sachet into a glass. Add 8-12 oz of water, stir, and enjoy with a straw. Alternatively, swirl the glass before the last couple sips as natural settling will occur. Take at least once daily (with or without food).

Our Medical Advisory Board formulated Postmenopause Essentials to match published research at dosages proven to deliver results for women. This is uncommon in the supplement world–brands typically sprinkle many ingredients in too-small quantities.

Manufactured in US-based facilities at FDA registered sites, with cGMP certifications.We use third-party testing for independent verification of our quality. Ingredients included are Generally Recognized as Safe (GRAS). Our products are: 

  • Non-GMO
  • Gluten-free
  • Vegetarian*
  • No artificial flavors or colors
  • No sugar added

*contains shellac, a natural resin sourced from the Lac beetle

Designed to replace multiple supplements with one comprehensive solution for your hormonal stage.

Science & Research

Formulated with Purpose. Backed by Science.

Every ingredient in Postmenopause Essentials was selected by our Medical Advisory Board to address the real health concerns women experience during postmenopause while also ensuring overall nutritional needs are met.

15

Immune biomarkers (proteins) positively responded [1]

98%

Loss of fat, not muscle; along with diet and exercise [2]

98%

Achieved normal stool consistency after 4 weeks [3]

7x

Improvement in facial wrinkle severity after 4 weeks vs placebo [4]

Enhanced Absorption

Lifestage Specific

Science Backed Ingredients

Comprehensive Formula

Published In:
[1] Inflammation (March 2023). [2] Current Therapeutic Research (Volume 59, Issue 6, June 1998). [3] Probiotics and Antimicrobial Proteins (June 2020). [4] Journal of Clinical Medicine (November 2022).

What’s inside

Our clinically backed ingredients

Clear plastic cup with red liquid on a red background

MAXIMAL ABSORPTION. GENUINE DAILY ENJOYMENT.

What’s inside

Our clinically backed ingredients

Botanicals & Other Clinically-Backed Ingredients

After menopause, cellular aging accelerates and muscle mass naturally declines. We've included 200mcg of highly bioavailable Chromax® chromium picolinate to support lean muscle mass and metabolism, 100mg hobamine® 2-HOBA for cellular health and healthy aging, and 300mg Pomella® pomegranate extract clinically shown to hydrate skin and provide a small reduction in facial wrinkle alongside its heart healthy benefits. This comprehensive approach replaces multiple anti-aging and longevity supplements with one science-backed formula.

Ingredients Glossary
Clear plastic cup with red liquid on a red background Chromium (as Chromium Picolinate)
Clear plastic cup with red liquid on a red background Pomegranate Extract
Clear plastic cup with red liquid on a red background 2-HOBA

Probiotics

Our clinically studied probiotic strain of Bacillus coagulans Unique-IS2® supports digestive health and stool regularity, and promotes a healthy microbiome that may help with nutrient availability for the gut cells and overall nutrient absorption. Gut health affects hormone metabolism and the gut-brain connection—the communication pathway between your digestive system and brain that influences mood, stress response, and energy levels. Since your gut produces about 90% of your body's serotonin (a key mood neurotransmitter), supporting gut health directly impacts how you feel.

Ingredients Glossary
Clear plastic cup with red liquid on a red background Bacillus Coagulans

Vitamins & Minerals

Postmenopausal women have specific nutritional needs including those around bone health, so we provide comprehensive support including Menatto® - clinically studied K2 that works synergistically with vitamin D3, calcium citrate, and magnesium citrate to support bone density and cardiovascular health. Our formula provides bioavailable B-vitamins for energy metabolism as brain health and cellular processes become more important to support on a daily basis. This targeted nutritional complex eliminates the need for separate multivitamins, bone health supplements, and vitamin D formulas while providing specialized support for postmenopausal wellness.

Ingredients Glossary
Clear plastic cup with red liquid on a red background Vitamin K2
Clear plastic cup with red liquid on a red background Vitamin D3
Clear plastic cup with red liquid on a red background B-Vitamin Complex

Electrolytes

Our electrolyte blend (200mg sodium, 100mg potassium) supports optimal hydration and nervous system function when made into a beverage. Unlike hydration products with up to 1000mg of sodium, our formulation delivers an amount more suitable without excess sodium that may cause bloating.

Ingredients Glossary
Clear plastic cup with red liquid on a red background Sodium
Clear plastic cup with red liquid on a red background Potassium

How we compare

Biologica Essentials deliver comprehensive nutrition and targeted relief, all designed for the woman who you are today.

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Greens

Multivitamins

Probiotics

Designed For Female Lifestages

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Alleviates Key Health Concerns

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Essential Vitamins and Minerals

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Clinically Studied Dosages

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Supports Gut Health

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Electrolytes

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WHAT’S BEHIND OUR LIFESTAGE FORMULATIONS

THE SCIENCE OF MENOPAUSE

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After menopause, reduced estrogen levels negatively affect bone density, cardiac health, the ability to preserve muscle mass, as well as brain health. Postmenopause Essentials provides targeted nutrition to increase health quality in this hormonal stage, with a suite of critical nutrients and clinically backed ingredients supporting lean muscle mass, bone health, brain and heart health, and cellular protection for healthy aging.

Learn more — hormones 101

TASTES LIKE A DAILY RITUAL SHOULD

We tested dozens of flavors because your daily supplement shouldn't taste like medicine. As a result of this research, and without any sugar, each Biologica Essential comes in a range of indulgent, flavor-forward options from fruit from real farms—think bright, juicy, and never too sweet. It's the kind of daily ritual you'll actually want to maintain.

Product Reviews

4.2
Rated 4.2 out of 5 stars
Based on 91 reviews
77%would recommend this product
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91 reviews
  • LE
    Liza E.
    I recommend this product
    Rated 5 out of 5 stars
    6 hours ago
    Inquiry

    Is this safe to drink? I have high blood pressure & anxiety. I want try but not sure if safe. Kindly advise. Thank you

    Was this helpful?
    Biologica Wellness
    22 seconds ago

    We'd always recommend checking with your healthcare provider before starting any new supplement,  they know your full medical history. That said, feel free to share the full ingredient list with them: https://biologica.com/pages/ingredients

  • S
    Susan
    Verified Buyer
    Rated 3 out of 5 stars
    2 weeks ago
    Powder

    The powder doesn't dissolve well. I am constantly having to stir it so I don't just get a mouthful of powder especially at the end of the drink. The taste is good though.

    Was this helpful?
    Biologica Wellness
    1 week ago

    Thanks for the feedback and I really appreciate you taking the time.

    Since our formula is naturally effervescent, some settling is normal. Many customers also find it helpful to drink it with a straw. You can also try mixing it into a smoothie or juice if you prefer. When preparing it, pouring the powder in slowly can help reduce the fizz and improve mixing.

    Our founder also shared a quick video explaining why this happens and how to get the best experience: https://www.youtube.com/shorts/NyNTEI7IRU8

  • M
    Melissa
    I do not recommend this product
    Rated 1 out of 5 stars
    2 weeks ago
    1 Star

    Very gritty despite mixing and stirring it & i did not like the taste

    Was this helpful?
  • G
    Gilbert
    I do not recommend this product
    Rated 1 out of 5 stars
    4 weeks ago
    1 Star

    Cancel my subscription

    Was this helpful?
  • LM
    Lynette M.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    1 month ago
    Just started

    Just started, haven’t noticed a difference yet. I do like the taste and it is not sweet or too salty as some drinks with electrolytes are. I do wish it dissolved better, I shake and stir constantly and it is still gritty at the end. I even tried hot water first and then adding cold water—still settles at the bottom.

    Was this helpful?
    Biologica Wellness
    1 month ago

    We really appreciate you taking the time to share your feedback. Benefits build over time, and consistency is key. Each product is formulated for a specific hormonal lifestage, so the benefits can vary from person to person. While our goal is for you to notice improvements early on, the majority of the benefits come with continued, consistent use.

    The grittiness you're experiencing is completely normal and is a result of our effervescent formula, which is designed to help the body more easily absorb the ingredients. For the best experience, we recommend drinking it with a straw and stirring before each sip. You can also mix it with smoothies or juice—just pour the powder in slowly to allow the natural fizz to settle. Our founder explains more in this short video: https://www.youtube.com/shorts/NyNTEI7IRU8

Got more questions?

Frequently Asked Questions

The formula was designed to contain ingredients that focus on and support areas like bone health, heart health, cellular longevity, and healthy aging, common health priorities in postmenopause. While there is nothing in the formulation that would interact directly with HRT, we always recommend discussing any new supplements with your qualified healthcare provider, including if you're on hormone therapy.

Our formula includes bone-supporting nutrients like vitamin D3, vitamin K2, calcium, and magnesium. However, for significant bone health concerns, we recommend working with your healthcare provider on a comprehensive approach that may include exercise, diet, and medical evaluation.

Chromium picolinate (Chromax®) in our formula helps support lean muscle mass and the body's metabolism, when combined with adequate protein and regular weight bearing exercise. Supporting lean muscle mass becomes especially important after menopause when declining estrogen makes it harder to maintain. Chromium is a mineral the body needs throughout life that works by helping your body unlock energy from food, supporting healthy blood sugar levels already in the normal range. When we age, and estrogen levels naturally decline, making sure we are getting appropriate levels of chromium can help support our metabolism by converting our nutrition into the fuel our muscles need, to stay lean.

Many women find that combining GLP-1 medications with targeted nutrition provides comprehensive support for their health goals. Our formula bridges critical nutritional gaps—combining metabolism-supporting chromium with calcium, magnesium, and vitamin D3—to help preserve muscle quality and bone integrity during significant weight shifts. However, we always recommend discussing any new supplements with your healthcare provider, especially when taking prescription medications, to ensure the best approach for your individual situation.

Generally yes, but we always recommend reviewing your complete supplement regimen with your healthcare provider. Postmenopause Essentials is designed to be comprehensive enough to replace multiple individual supplements while providing targeted support for this life stage.

Unlike generic vitamins for 50+ years old women, Postmenopause Essentials is specifically formulated for postmenopausal women with a full spectrum of essential vitamins and minerals, as well a clinically backed ingredients like chromium picolinate for muscle support, 2-HOBA for cellular health, and probiotics for gut health. Plus, our effervescent format provides quality absorption, offers an easier alternative to swallowing multiple pills, and delivers a delicious tasting beverage.

Menopause marks a day in time, which occurs 12 months after your final period, this is when you're officially postmenopausal. However, if you're still experiencing some perimenopausal symptoms, which can be common, you might benefit from continuing Midlife Essentials until those settle. You can always switch formulas as your needs evolve—that's exactly why we created stage-specific support.

Our B-vitamin complex and chromium support natural energy metabolism by helping your body efficiently convert food into fuel, rather than providing stimulants. Most women notice sustained mental energy improvements within 2-4 weeks as their nutrient levels optimize, without any jittery feelings.

Rather than promising to reverse aging, we focus on supporting the biological processes that promote healthy aging—like cellular protection with 2-HOBA, muscle mass maintenance with chromium, and skin health with pomegranate extract. It's about aging powerfully, not trying to stop the natural process.

Our formulas are designed to complement your existing health routine. However, we always recommend consulting with your healthcare provider before starting any new supplement, especially if you're taking medications or have specific health conditions. They know your medical history best.

The benefits of Postmenopause build over time to support long-term vitality. Most women notice increased energy and stamina within a few weeks as electrolytes and B-vitamins replenish the system. By weeks 5–8, hobamine® supports cellular health to combat oxidative stress, while months 2 and 3 introduce visible improvements in skin radiance and metabolic efficiency. Because bone density and metabolic health require consistent nourishment, the most significant results—including the full protective effects of Calcium, D3, and K2—are realized after 90 days.
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Citations

15 Immune biomarkers (proteins) positively responded

"Inflammation Biomarker Response to Oral 2-Hydroxybenzylamine (2-HOBA) Acetate in Healthy Humans."

  • Lead Author: John A. Rathmacher, Ph.D.
  • Published In: Inflammation (March 2023).
  • The 15 Proteins Statistic: 15 specific immune proteins (biomarkers) showed a significant, positive response to Hobamine compared to the placebo group in the Olink® Targeted Inflammation Panel.

98% Loss of fat, not muscle; along with diet and exercise

"A randomized, double-masked, placebo-controlled study of the effects of chromium picolinate supplementation on body composition: A replication and extension of a previous study."

  • Authors: Kaats, G. R., Blum, K., Pullin, D., Keith, S. C., & Wood, R.
  • Published In: Current Therapeutic Research (Volume 59, Issue 6, June 1998).
  • The 98% Statistic Explained: if you lose 7.8 kg total and 7.7 kg of that is fat, then 98.7% of the weight lost was fat. This is where the "98%" claim originates.

Achieved normal stool consistency after 4 weeks

"Bacillus coagulans Unique IS2 in Constipation: A Double-Blind, Placebo-Controlled Study."

  • Authors: Madempudi, R. S., Neelamraju, J., Ahire, J. J., Gupta, S. K., & Shukla, V. K.
  • Published In: Probiotics and Antimicrobial Proteins (June 2020).
  • The 98% Statistic: at the start of the study, 0% of the participants had normal stool consistency. By the end of 4 weeks, 98% of those in the probiotic group achieved "normal" stool form (defined as Type 3, 4, or 5 on the Bristol Stool Chart).

7x Improvement in facial wrinkle severity after 4 weeks vs placebo

"Prospective Randomized Double-Blind Placebo-Controlled Study of Oral Pomegranate Extract on Skin Wrinkles, Biophysical Features, and the Gut-Skin Axis."

  • Lead Author: Mincy Chakkalakal and Dr. Raja Sivamani.
  • Published In: Journal of Clinical Medicine (November 2022).
  • The 7x Improvement: the 7x statistic is derived from the following results: Pomella Group: Saw a 6.2% reduction in wrinkle severity; Placebo Group: Saw a 1.0% increase (worsening) in wrinkle severity. When comparing the 6.2% improvement in the Pomella group to the 0.8%–1.0% change typical of the placebo group in these imaging trials, the supplement group's results were roughly 7 times greater in magnitude.

Postmenopause Essentials

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